Relative deficiency of intracellular potassium

ions in relation to the health and diseases

1. Dai, J.P. (2022) Why Are There So Many Puzzles in Fighting against COVID-19 Pandemic? Natural Science, 14, 424-433. https://doi.org/10.4236/ns.2022.1410036

17. Dai, J.P. (2022) The Core Mechanism of Natural Selection: How the Natural Cycle of Potassium Resources Affects the Biological Evolution and the Change of Human Society. Natural Science, 14, 434-440. https://doi.org/10.4236/ns.2022.1410037

13. Dai, J.P. (2022) The Relative Deficiency of Potassium Ions in Nerve Cells Causes Abnormal Functions and Neurological and Mental Diseases. Natural Science, 14, 441-447. https://doi.org/10.4236/ns.2022.1410038

1. Dai, J.P. (2022) The Core Mechanism of Traditional Medicine Is the Rational and Effective Use of Potassium Ions. Natural Science, 14, 483-491. https://doi.org/10.4236/ns.2022.1411042

1. Dai, J.P. (2022) The Continuous Relative Deficiency of Intracellular Potassium Is a Core Mechanism for the Occurrence and Metastasis of Tumor Cancer Cells. Natural Science, 14, 492-496. https://doi.org/10.4236/ns.2022.1411043

12. Dai, J.P. (2022) Relative Deficiency of Intracellular Potassium in Relation to the Functional Changes and Diseases in Non-Nervous System. Natural Science, 14, 497-502. https://doi.org/10.4236/ns.2022.1411044

It was found that intracellular simulated biophoton stimulation in a single nerve cell led to the transsynaptic signal transmission in mouse hippocampal neural circuits.

Na Liu, Zhuo Wang and Jiapei Dai. Intracellular simulated biophoton stimulation

and transsynaptic signal transmission. Appl. Phys. Lett. 121, 203701 (2022); https://doi.org/10.1063/5.0128956

Development of a new technology (T-Dai) for real-time detection of viruses in aerosols with weak light imaging based on Tesla Discharge.

Zuxin Li，Chengming Xia，Yi Tian, Beilei Zhang，Wan Zhou，Na Liu，Qiao Wei，Jinzhong Li，Cong Chen，Linhua Chen，Zhuo Wang, Yan Sun, Chang Li，Dong Yang，Wangyang Yu，Meng Liu，Jiapei Dai. Real-time detection of viruses in aerosols with weak light imaging based on Tesla Discharge. Appl. Phys. Lett. 121, 060601 (2022); https://doi.org/10.1063/5.0104527

Using ultraweak biophoton imaging system (UBIS), we identified a delayed functional neural circuit injury after cerebral ischemia-reperfusion, which provides a new functional evaluation method for studying the mechanism of cerebral ischemia-reperfusion injury and developing new drugs.

Chai W, Zhang C, Dai J. Biophoton imaging identification of delayed functional neural circuit injury after cerebral ischemia-reperfusion. J Neurosci Methods. 2022 Feb 1;367:109438. DOI: 10.1016/j.jneumeth.2021.109438

Discovery of a quantum mechanism of neurotransmitter action, which may provide a new idea to elucidate brain functions and to develop “quantum drugs” and “quantum therapies”

Han Z, Chai W, Wang Z, Xiao F, Dai J. Quantum energy levels of glutamate modulate neural biophotonic signals. Photochem Photobiol Sci. 2021 Mar;20(3):343-356.

DOI:10.1007/s43630-021-00022-0

It is found that biophotonic activity and transmission mediated by mutual actions of neurotransmitters are involved in the origin and altered states of consciousness, and a new concept of "photon brain" is proposed.

Chai W, Han Z, Wang Z, Li Z, Xiao F, Sun Y, Dai Y, Tang R, Dai J. Biophotonic Activity and Transmission Mediated by Mutual Actions of Neurotransmitters are Involved in the Origin and Altered States of Consciousness. Neurosci Bull. 2018 Jun;34(3):534-538. doi:10.1007/s12264-018-0215-9

We found that glutamate-induced biophotonic activities and transmission in the brain present a spectral redshift from animals to humans. This brain property may be a key biophysical basis for explaining high intelligence in humans.

1. Wang Z, Wang N, Li Z, Xiao F, Dai J. Human high intelligence is involved in spectral redshift of biophotonic activities in the brain. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8753-8.

4. Dai J, Wang Z, Li Z, Xiao F. Reply to Salari et al.: Toward understanding the deep mechanisms regarding the biophotons related to human intelligence. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5542-3.

http://www.the-scientist.com/?articles.view/articleNo/47099/title/Do-Brighter-Species--Brains-Emit-Redder-Light-/

http://www.cankaoxiaoxi.com/science/20160813/1266801.shtml

We found a significant temperature-dependent increase in biophotonic activities in rat and bullfrog (rana catesbiana) retinas. These findings suggest that the photon-like component of discrete dark noise may be caused not by a direct contribution of the thermal activation of rhodopsin but rather by an indirect thermal induction of biophotonic activities, which then activate the retinal chromophore of rhodopsin. Therefore, this study suggests a possible solution regarding the thermal activation energy barrier for discrete dark noise, which has been debated for almost half a century.

Li Z, Dai J. Biophotons Contribute to Retinal Dark Noise. Neurosci Bull. 2016;32(3):246-52.

• An ultraweak photon imaging system (UBIS) and the related analytical methods have been developed for detecting the biophotons spatiotemporally.

• Jiapei Dai, Rendong Tang, Chao Wang. Automatic ultraweak biophoton imaging system and the method of operation. 2014.1.29-2033.10.30。ZL201310524951.4 (patent）.

1. Rendong Tang,Jiapei Dai.Photonic information extraction of utraweak emission imaging based on watershed algorithm. 2013,4(1):202-208.

Tang R, Dai J. Spatiotemporal imaging of glutamate-induced biophotonic activities and transmission in neural circuits. PLoS One. 2014, 15;9(1):e85643.

The characteristic changes of biophotonic activities induced by glutamate were found and biophotonic transmission was also verified, which may provide a new idea for the establishment of quantum brain mechanism.

Tang R, Dai J. Spatiotemporal imaging of glutamate-induced biophotonic activities and transmission in neural circuits. PLoS One. 2014, 15;9(1):e85643.

1. Tang R, Dai J. Biophoton signal transmission and processing in the brain. J Photochem Photobiol B. 2014,139:71-5.

1.  

2. A new neuropathological change, called as axonal leakage, was identified in the AD brains, which may be association with the development of AD related to AD risk factors such as stroke and diabetic encephalopathy.

4. Zhou Y, Luo Y, Dai J. Axonal and Dendritic Changes are Associated with Diabetic Encephalopathy in Rats: An Important Risk Factor for Alzheimer's Disease. J Alzheimers Dis.2013,34(4):937-47.

12. Zhang Q, Gao T, Luo Y, Chen X, Gao G, Gao X, Zhou Y, Dai J.Transient focal cerebral ischemia/reperfusion induces early and chronic axonal changes in rats: its importance for the risk of Alzheimer’s disease. Plos One 2012, 7(3): e33722.

2. Xiao A, He J, Wang Q, Luo Y, Sun Y, Zhou Y, Guan Y, Lucassen P, Dai J. The origin and development of plaques and phosphorylated tau are associated with axonopathy in Alzheimer’s disease. Neurosci Bull 2011, 27(5): 287-299.

An in situ biophoton autography technique was developed, which resulted in the discovery of biophotonic conduction along the neural fibers.

Sun Y, Wang C, Dai J. Biophotons as neural communication signals demonstrated by in situ biophoton autography. Photochem. Photobiol. Sci. 2010, 9:315-322.